NeuroVascular Research Intelligence Platform — Welcome, Dr. Osama
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5
Articles in Databank
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8
Hypotheses Generated
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1
Methodologies Catalogued
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0
Manuscripts Analysed
📊 Field Coverage by Subspecialty
Cerebrovascular Disease5
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🌍 Geographic Distribution
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📰 Weekly Literature Report
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🔍 PubMed Search Configuration
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🗄️ Article Databank
Centralized repository of all saved neurovascular & neurointerventional literature
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⚗️ Methodology Factory
Auto-catalogued research methodologies from your databank — select combinations to explore connections
📌 Pinned Articles from Databank 1
Brain frailty on penumbral salvage following successful reperfusion in MeVO stroke via col…
2026
📋 Methodology Registry
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Select 2–4 methodologies to explore how they can be combined in a novel research design.
⚡ Combined Research Design Output
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💡 Hypothesis Generator & Idea Exhibition
Identify research gaps and generate testable hypotheses based on your databank
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🗺️ Identified Research Gaps
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18 gaps
🤖 AI/Technology Gap🤖 Auto-suggested
AI validation and clinical integration gap for: Protective Effect of Chinese Herbal Medicine on Cerebral Ischemia-Reperfusion In...
Auto-extracted from: "Protective Effect of Chinese Herbal Medicine on Cerebral Ischemia-Reperfusion Injury by Regulating Ferroptosis.". Pattern detected: "ai". This study's limitations suggest an unmet need in the field that warrants targeted investigation.
Source study:Protective Effect of Chinese Herbal Medicine on Cerebral Ischemia-Reperfusion Injury by Re...
3/27/2026
🤖 AI/Technology Gap🤖 Auto-suggested
AI validation and clinical integration gap for: Emerging role of cell membrane-coated nanoparticles in targeted therapy for brai...
Auto-extracted from: "Emerging role of cell membrane-coated nanoparticles in targeted therapy for brain disorders.". Pattern detected: "ai". This study's limitations suggest an unmet need in the field that warrants targeted investigation.
Source study:Emerging role of cell membrane-coated nanoparticles in targeted therapy for brain disorder...
3/27/2026
🤖 AI/Technology Gap🤖 Auto-suggested
AI validation and clinical integration gap for: Transplantation of hPSC-Derived Pericyte-Enriched Vascular Assemblies Restores C...
Auto-extracted from: "Transplantation of hPSC-Derived Pericyte-Enriched Vascular Assemblies Restores Cerebral Perfusion in the Context of Perm". Pattern detected: "ai". This study's limitations suggest an unmet need in the field that warrants targeted investigation.
Source study:Transplantation of hPSC-Derived Pericyte-Enriched Vascular Assemblies Restores Cerebral Pe...
3/27/2026
🤖 AI/Technology Gap🤖 Auto-suggested
AI validation and clinical integration gap for: Microglial Inhibition Promotes Proliferation and Differentiation of Neural Stem ...
Auto-extracted from: "Microglial Inhibition Promotes Proliferation and Differentiation of Neural Stem Cells via STAT3/SDF-1/CXCR4 Signaling Pa". Pattern detected: "model". This study's limitations suggest an unmet need in the field that warrants targeted investigation.
Source study:Microglial Inhibition Promotes Proliferation and Differentiation of Neural Stem Cells via ...
3/27/2026
🔄 Translational Gap🤖 Auto-suggested
Clinical translation needed for preclinical findings on: LUNG FUCTION IMPAIRMENT FOLLOWING CEREBRAL ISCHEMIC STROKE: PATHOPHYSIOLOGY, MEC...
Auto-extracted from: "LUNG FUCTION IMPAIRMENT FOLLOWING CEREBRAL ISCHEMIC STROKE: PATHOPHYSIOLOGY, MECHANISMS, AND CLINICAL CHALLENGES.". Pattern detected: "animal model". This study's limitations suggest an unmet need in the field that warrants targeted investigation.
Auto-extracted from: "Inhibition of Endothelial ALOX12 Mitigates Cerebral Ischemia-Reperfusion Injury by Suppressing 12-HETE.". Pattern detected: "nfl". This study's limitations suggest an unmet need in the field that warrants targeted investigation.
Source study:Inhibition of Endothelial ALOX12 Mitigates Cerebral Ischemia-Reperfusion Injury by Suppres...
3/27/2026
🌱 Emerging Gap🤖 Auto-suggested
Validated clinical biomarker lacking for: Polymersomes preventing brain infiltration of CD177+ neutrophils to mitigate hem...
Auto-extracted from: "Polymersomes preventing brain infiltration of CD177+ neutrophils to mitigate hemorrhagic transformation post-tPA thrombo". Pattern detected: "protein". This study's limitations suggest an unmet need in the field that warrants targeted investigation.
Source study:Polymersomes preventing brain infiltration of CD177+ neutrophils to mitigate hemorrhagic t...
3/27/2026
🤖 AI/Technology Gap🤖 Auto-suggested
AI validation and clinical integration gap for: Pathologically Confirmed Symptomatic Carotid Webs: Histopathological Features an...
Auto-extracted from: "Pathologically Confirmed Symptomatic Carotid Webs: Histopathological Features and Long-Term Surgical Outcomes.". Pattern detected: "ai". This study's limitations suggest an unmet need in the field that warrants targeted investigation.
Source study:Pathologically Confirmed Symptomatic Carotid Webs: Histopathological Features and Long-Ter...
3/27/2026
🤖 AI/Technology Gap🤖 Auto-suggested
AI validation and clinical integration gap for: Symptom Phenotypes and Treatment Failure of Dural Venous Sinus Stenting in Idiop...
Auto-extracted from: "Symptom Phenotypes and Treatment Failure of Dural Venous Sinus Stenting in Idiopathic Intracranial Hypertension: A Natio". Pattern detected: "ai". This study's limitations suggest an unmet need in the field that warrants targeted investigation.
Source study:Symptom Phenotypes and Treatment Failure of Dural Venous Sinus Stenting in Idiopathic Intr...
3/27/2026
🔬 Methodological Gap🤖 Auto-suggested
Prospective multi-center evidence needed: Brain frailty on penumbral salvage following successful reperfusion in MeVO stro...
Auto-extracted from: "Brain frailty on penumbral salvage following successful reperfusion in MeVO stroke via collateral impairment.". Pattern detected: "retrospective". This study's limitations suggest an unmet need in the field that warrants targeted investigation.
Source study:Brain frailty on penumbral salvage following successful reperfusion in MeVO stroke via col...
3/27/2026
🔍 Known Gap
Long-term outcomes of flow diversion in fusiform aneurysms
Most RCTs follow up for ≤1 year. The 5–10 year occlusion durability and retreatment rates for pipeline-treated fusiform aneurysms remain poorly characterized, especially in elderly patients.
3/27/2026
🔍 Known Gap
Optimal timing of thrombectomy in wake-up stroke
Evidence on the optimal imaging selection criteria and time window for thrombectomy in wake-up stroke remains heterogeneous. Studies on MR NIHSS mismatch in low-volume centers are lacking.
3/27/2026
🔍 Known Gap
AVM embolization as sole curative treatment in Spetzler-Martin Grade I–II
The curative role of liquid embolic agents (Onyx, PHIL) as monotherapy for low-grade AVMs is understudied in prospective, controlled settings.
3/27/2026
🌍 LMIC Gap
Thrombectomy outcomes in low- and middle-income countries
Nearly all landmark RCTs for mechanical thrombectomy were conducted in high-income countries. Outcome data from LMICs with limited device availability and delayed imaging is virtually absent.
3/27/2026
🌱 Emerging Gap
Biomarker-guided decision making for aneurysm treatment timing
No validated serum or imaging biomarker reliably predicts aneurysm rupture risk within a clinically actionable time window to guide urgency of treatment.
3/27/2026
🔬 Methodological Gap
Standardized outcome metrics in neurointerventional trials
Heterogeneity in reported outcomes (mRS, NIHSS, imaging) limits meta-analysis. A core outcome set for neurointerventional trials has not been established.
3/27/2026
🤖 AI/Technology Gap
AI-assisted real-time procedure guidance in thrombectomy
While AI has shown promise in imaging analysis, its role in real-time intraprocedural guidance — including automated device selection and trajectory planning — remains largely unexplored.
3/27/2026
🔄 Translational Gap
Clot composition analysis and device selection for thrombectomy
The relationship between clot histology (fibrin-rich vs platelet-rich vs mixed) and optimal thrombectomy device/technique selection is underinvestigated in prospective studies.
3/27/2026
No gaps match your filter. Try auto-suggesting from the databank or add one manually.
💡 Hypothesis Exhibition Gallery
💡 Mechanical Thrombectomy Outcomes — Effectiveness Comparison (A vs B)
3/27/2026
In patients undergoing mechanical thrombectomy outcomes, a prospective comparative study evaluating standard technique A versus novel technique B would address the existing gap of limited level-I evidence in this subspecialty and could potentially change current treatment guidelines.
Evidence Gap: Real-world registry data from low- and middle-income countries is virtually absent.
💡 Flow Diversion Devices — Effectiveness Comparison (A vs B)
3/27/2026
In patients undergoing flow diversion devices, a prospective comparative study evaluating standard technique A versus novel technique B would address the existing gap of limited level-I evidence in this subspecialty and could potentially change current treatment guidelines.
Evidence Gap: Real-world registry data from low- and middle-income countries is virtually absent.
💡 Mechanical Thrombectomy Outcomes — Effectiveness Comparison (A vs B)
3/27/2026
We hypothesize that implementing advanced neuroimaging-guided patient selection criteria for mechanical thrombectomy outcomes will significantly improve procedure success rates (mTICI ≥2b) and 90-day functional independence (mRS 0–2) compared to current standard selection protocols.
Evidence Gap: Most existing studies are single-center retrospective with follow-up limited to 30–90 days.
💡 AI / Machine Learning in Neuroradiology — Technical Innovation Hypothesis
3/27/2026
The integration of artificial intelligence and machine learning algorithms into pre-procedural planning for ai / machine learning in neuroradiology represents a testable hypothesis: AI-assisted case planning reduces procedure time, fluoroscopy dose, and contrast volume while improving technical success rates versus conventional planning.
Evidence Gap: Most existing studies are single-center retrospective with follow-up limited to 30–90 days.
We hypothesize that implementing advanced neuroimaging-guided patient selection criteria for mechanical thrombectomy outcomes will significantly improve procedure success rates (mTICI ≥2b) and 90-day functional independence (mRS 0–2) compared to current standard selection protocols.
Evidence Gap: Real-world registry data from low- and middle-income countries is virtually absent.
💡 Mechanical Thrombectomy Outcomes — Effectiveness Comparison (A vs B)
3/27/2026
In patients undergoing mechanical thrombectomy outcomes, a prospective comparative study evaluating standard technique A versus novel technique B would address the existing gap of limited level-I evidence in this subspecialty and could potentially change current treatment guidelines.
Evidence Gap: No prospective RCT has evaluated this question with standardized outcome metrics (mRS, NIHSS).
💡 Tandem Occlusion Treatment Strategy — Predictive / Prognostic Factor
3/27/2026
The integration of artificial intelligence and machine learning algorithms into pre-procedural planning for tandem occlusion treatment strategy represents a testable hypothesis: AI-assisted case planning reduces procedure time, fluoroscopy dose, and contrast volume while improving technical success rates versus conventional planning.
Evidence Gap: No prospective RCT has evaluated this question with standardized outcome metrics (mRS, NIHSS).
💡 Cerebrovascular Disease — Effectiveness Comparison (A vs B)
3/27/2026
In patients undergoing cerebrovascular disease, a prospective comparative study evaluating standard technique A versus novel technique B would address the existing gap of limited level-I evidence in this subspecialty and could potentially change current treatment guidelines.
Evidence Gap: Long-term (≥3 year) imaging follow-up is missing in most published series.
No hypotheses generated yet. Use the generator above to create your first hypothesis.
📝 Manuscript Formatter
Paste your manuscript and select a target journal to reformat it according to specific guidelines
Step 1 — Paste Your Manuscript
Step 2 — Select Target Journal
Stroke
Q1
AHA · IF 6.18
J. NeuroInterventional Surgery
Q1
BMJ / SNIS · IF 4.4
Stroke: Vascular & Interventional Neurology
Q2
AHA (OA) · IF 3.1 · OA
American J. Neuroradiology
Q2
ASNR · IF 3.4
Interventional Neuroradiology
Q2
SAGE / ESMINT · IF 1.8
International Journal of Stroke
Q1
SAGE / WSO · IF 6
Journal of Stroke
Q1
Korean Stroke Society (OA) · IF 8.2 · OA
Stroke & Vascular Neurology
Q1
BMJ / CSA (OA) · IF 4.4 · OA
Cerebrovascular Diseases
Q2
Karger · IF 2.2
Translational Stroke Research
Q1
Springer Nature · IF 6.3
Frontiers in Neurology
Q2
Frontiers (OA) · IF 2.7 · OA
Neurointervention
Q2
KSIN (OA) · IF 1.6 · OA
Formatted Output
🔍 Acceptance Guidance & Peer Review Simulator
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📋 Manuscript Details
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Article Detail
🔬 Lab-to-Hospital: Translational Research Pool
Continuously updated pool of basic & translational neurovascular research — bridging bench findings to clinical application
🔍 Weekly PubMed Scan — Basic & Translational Research
🧪 Translational Research Pool
112 translational studies | Last updated: 3/27/2026
112
Total Studies
15
Animal Studies
4
In Vitro / Cellular
51
High Translational Potential
Searching PubMed for translational research...
In Vivo — Rodent Model
Inhibition of Endothelial ALOX12 Mitigates Cerebral Ischemia-Reperfusion Injury by Suppressing 12-HETE.
👤 Wang T, Wang J, Wang G, Wang D, Wang T, Wang X et al.📗 Free Radic Biol Med (2026)🟢 High Potential🌍 LMIC: Medium🔗 10.1016/j.freeradbiomed.2026.03.054
Translational — Mixed (Lab + Clinical)
LUNG FUCTION IMPAIRMENT FOLLOWING CEREBRAL ISCHEMIC STROKE: PATHOPHYSIOLOGY, MECHANISMS, AND CLINICAL CHALLENGES.
👤 Somogyi P, Somogyi B, Somogyi E, Somogyi F📗 Respir Physiol Neurobiol (2026)🟢 High Potential🌍 LMIC: Medium🔗 10.1016/j.resp.2026.104567
Translational — Mixed (Lab + Clinical)
Microglial Inhibition Promotes Proliferation and Differentiation of Neural Stem Cells via STAT3/SDF-1/CXCR4 Signaling Pathway in Hypoxic-Ischemic Encephalopathy.
👤 Ding A, Ding G, Ding M, Ding L, Ding J, Ding T et al.📗 Glia (2026)🟡 Medium Potential🌍 LMIC: Medium🔗 10.1002/glia.70149
Translational — Mixed (Lab + Clinical)
Transplantation of hPSC-Derived Pericyte-Enriched Vascular Assemblies Restores Cerebral Perfusion in the Context of Permanent Brain Ischemia.
👤 Zhou J, Zhou P, Zhou Y, Zhou T, Zhou X, Zhou Q et al.📗 Adv Healthc Mater (2026)🟢 High Potential🌍 LMIC: Medium🔗 10.1002/adhm.202600014
Translational — Mixed (Lab + Clinical)
Emerging role of cell membrane-coated nanoparticles in targeted therapy for brain disorders.
👤 Kumari V, Kumari M, Kumari K, Kumari N, Kumari N, Kumari M et al.📗 Biomater Adv (2026)🔴 Low Potential🌍 LMIC: Medium🔗 10.1016/j.bioadv.2026.214822
Translational — Mixed (Lab + Clinical)
Protective Effect of Chinese Herbal Medicine on Cerebral Ischemia-Reperfusion Injury by Regulating Ferroptosis.
👤 Luo S, Luo J, Luo L, Luo J, Luo Y📗 Drug Des Devel Ther (2026)🔴 Low Potential🌍 LMIC: Medium🔗 10.2147/DDDT.S563534
Translational — Mixed (Lab + Clinical)
Application of new media-based home nursing intervention for stroke-related depression patients: a retrospective cohort study.
👤 Huang X, Huang X, Huang X, Huang X, Huang L, Huang M📗 Front Public Health (2026)🔴 Low Potential🌍 LMIC: Medium🔗 10.3389/fpubh.2026.1775705
Translational — Mixed (Lab + Clinical)
Cystinosin regulates Na+/H+ exchanger 3 trafficking and function in kidney proximal tubular cells.
👤 Khare V, Khare JC, Khare M, Khare CJ, Khare C, Khare X et al.📗 EMBO Rep (2026)🟢 High Potential🌍 LMIC: Medium🔗 10.1038/s44319-026-00736-1
Translational — Mixed (Lab + Clinical)
[Research progress on the preventive and therapeutic effects of hydrogen in oxidative stress-induced pulmonary diseases].
👤 Liu Z, Liu P, Liu Y, Liu W📗 Zhonghua Wei Zhong Bing Ji Jiu Yi Xue (2026)🟢 High Potential🌍 LMIC: Medium🔗 10.3760/cma.j.cn121430-20250611-00330
Translational — Mixed (Lab + Clinical)
GFAP+ FOXF2+ ependymal cells promote blood-brain barrier repair via DLL4-NOTCH signaling after neural injury.
👤 Xie Q, Xie H, Xie X, Xie S, Xie Q, Xie M et al.📗 Proc Natl Acad Sci U S A (2026)🟡 Medium Potential🌍 LMIC: Medium🔗 10.1073/pnas.2520352123
Translational — Mixed (Lab + Clinical)
Pathophysiological roles of neural stem cells in neuropsychiatric diseases: from plasticity to pharmacological targeting.
👤 Li YY, Li XY, Li YJ, Li I, Li Y, Li Z et al.📗 Acta Pharmacol Sin (2026)🔴 Low Potential🌍 LMIC: Medium🔗 10.1038/s41401-026-01779-9
Translational — Mixed (Lab + Clinical)
Animal Models for Long-Term Functional Recovery and Rehabilitation After Ischemic Stroke: Beyond Acute Neuroprotection.
👤 Zhang Y, Zhang Z, Zhang R, Zhang X, Zhang S, Zhang J et al.📗 J Vis Exp (2026)🟢 High Potential🌍 LMIC: Medium🔗 10.3791/69884
In Vivo — Rodent Model
Self-Assembling Hydrogel for Controlled Release of bFGF and Ang-1 Mimetic Peptide Promotes Neurovascular Repair in Ischemic Stroke Rats.
👤 Nie A, Nie W, Nie N, Nie R, Nie R, Nie C et al.📗 J Biomed Mater Res A (2026)🟡 Medium Potential🌍 LMIC: Medium🔗 10.1002/jbm.a.70063
Translational — Mixed (Lab + Clinical)
Trousseau's syndrome with cerebral infarction as the first manifestation.
👤 Zeng X, Zeng C, Zeng Y, Zeng Y, Zeng M, Zeng Y et al.📗 Am J Transl Res (2026)🟢 High Potential🌍 LMIC: Medium🔗 10.62347/IGUJ8639
In Vitro (Cell/Tissue)
GJA5 and ATP1A1 perturbations recapitulate inflammation-related beat irregularities in iPSC-based atrial myocardium tissue model.
👤 Hutschalik T, Hutschalik A, Hutschalik LL, Hutschalik M, Hutschalik F, Hutschalik LJAM et al.📗 Front Immunol (2025)🟢 High Potential🌍 LMIC: Medium🔗 10.3389/fimmu.2025.1719392
Translational — Mixed (Lab + Clinical)
Activation of TPC2 amplifies lysosome-mitochondria calcium transfer to regulate energetic stress responses.
👤 Ahmed S, Ahmed N, Ahmed KL, Ahmed KM, Ahmed JW, Ahmed PM et al.📗 bioRxiv (2026)🟡 Medium Potential🌍 LMIC: Medium🔗 10.64898/2026.03.03.709381
Translational — Mixed (Lab + Clinical)
PANoptosis and mitochondrial regulatory mechanisms in cerebral ischemia-reperfusion injury.
👤 Li L, Li C, Li Z, Li L, Li X, Li Y et al.📗 Front Physiol (2026)🟢 High Potential🌍 LMIC: Medium🔗 10.3389/fphys.2026.1759575
Translational — Mixed (Lab + Clinical)
Types of carotid stents and their associated strengths and limitations.
👤 Dubosq-Lebaz M, Dubosq-Lebaz WA, Dubosq-Lebaz PA, Dubosq-Lebaz CYC, Dubosq-Lebaz M, Dubosq-Lebaz EA📗 Semin Vasc Surg (2026)🟢 High Potential🌍 LMIC: Medium🔗 10.1053/j.semvascsurg.2025.11.002
Translational — Mixed (Lab + Clinical)
Intracellular mitochondrial transfer in ischemic stroke: Mechanisms and therapeutic application.
👤 Fu R, Fu Y, Fu Y, Fu Y, Fu M, Fu Z et al.📗 J Adv Res (2026)🟡 Medium Potential🌍 LMIC: Medium🔗 10.1016/j.jare.2026.03.037
Translational — Mixed (Lab + Clinical)
Biomarkers for advancing diagnosis and prognosis in stroke.
👤 Tiedt S, Tiedt A, Tiedt A, Tiedt P, Tiedt GM, Tiedt J et al.📗 Lancet Neurol (2026)🟢 High Potential🌍 LMIC: Medium🔗 10.1016/S1474-4422(25)00480-6
Translational — Mixed (Lab + Clinical)
Sodium pyruvate ameliorates cognitive dysfunction by expanding hippocampal endogenous neural stem cells in tBCCAO mice.
👤 He J, He L, He Z, He W, He B, He P et al.📗 Front Cell Dev Biol (2026)🟢 High Potential🌍 LMIC: Medium🔗 10.3389/fcell.2026.1782699
Translational — Mixed (Lab + Clinical)
Hypoxic-Ischemic Encephalopathy in Newborns: Pathophysiology, Early Identification, and Management.
Ischemia-Induced Post-Translational Modifications of GLT-1 Mediate Aberrant Trafficking and Impaired Glutamate Uptake.
👤 Gill SK, Gill KL, Gill M, Gill OV, Gill ACK📗 bioRxiv (2026)🟡 Medium Potential🌍 LMIC: Medium🔗 10.64898/2026.03.13.711603
In Vivo — Rodent Model
Multifunctional nanozyme therapy accelerates hematoma clearance and attenuates genome damage and senescence after intracerebral hemorrhage.
👤 Malojirao VH, Malojirao AM, Malojirao M, Malojirao AV, Malojirao PJ, Malojirao E et al.📗 bioRxiv (2026)🟡 Medium Potential🌍 LMIC: Medium🔗 10.64898/2026.03.12.711396
Translational — Mixed (Lab + Clinical)
Effects of Neuromuscular Electrical Stimulation on Swallowing Function for Post-Stroke Dysphagia: A Systematic Review and Meta-Analysis.
👤 Xu J, Xu J, Xu G📗 Int J Lang Commun Disord (2026)🔴 Low Potential🌍 LMIC: Medium🔗 10.1111/1460-6984.70230
Translational — Mixed (Lab + Clinical)
[Formononetin downregulates P53/SAT1/ACSL4 pathway-mediated ferroptosis to improve hypoxic-ischemic brain injury in neonatal mice].
👤 Guo T, Guo B, Guo X, Guo Y, Guo X, Guo J et al.📗 Nan Fang Yi Ke Da Xue Xue Bao (2026)🔴 Low Potential🌍 LMIC: Medium🔗 10.12122/j.issn.1673-4254.2026.03.14
Translational — Mixed (Lab + Clinical)
Huangqi Guizhi Wuwu Decoction promotes neuroprotection and functional recovery after ischemic stroke via activation of the PI3K/Akt/mTOR signaling pathway and modulation of microglial polarization.
👤 Pan X, Pan M, Pan H, Pan Y, Pan P📗 J Ethnopharmacol (2026)🟢 High Potential🌍 LMIC: Medium🔗 10.1016/j.jep.2026.121563
Translational — Mixed (Lab + Clinical)
Epigenetic Mechanisms Regulating Ferroptosis in Ischemic Stroke: From Pathogenesis to Therapeutic Targets.
👤 Gan J, Gan X, Gan J, Gan Z, Gan X, Gan Y et al.📗 Cell Mol Neurobiol (2026)🟢 High Potential🌍 LMIC: Medium🔗 10.1007/s10571-026-01718-6
Translational — Mixed (Lab + Clinical)
Efficacy and Safety of Cerebrolysin as an Adjunct to Mechanical Thrombectomy in Acute Ischemic Stroke: A Systematic Review and Meta-Analysis of Observational Studies.
👤 Afridi A, Afridi F, Afridi A, Afridi I, Afridi NE, Afridi U et al.📗 Brain Behav (2026)🔴 Low Potential🌍 LMIC: Medium🔗 10.1002/brb3.71252
Translational — Mixed (Lab + Clinical)
Deep neurotherapeutic strategy for ischemic stroke via focused ultrasound-enhanced delivery of curcumin-loaded antioxidant nanoliposomes.
👤 Su TY, Su MY, Su GT, Su WT, Su YL, Su C et al.📗 Biomater Sci (2026)🟡 Medium Potential🌍 LMIC: Medium🔗 10.1039/d5bm01596k
Translational — Mixed (Lab + Clinical)
Iridoids as Multi-Target Neuroprotective Agents for Ischemic Stroke: Mechanisms and Therapeutic Potential.
👤 Gao H, Gao M, Gao X, Gao Y, Gao W, Gao G et al.📗 Mini Rev Med Chem (2026)🟢 High Potential🌍 LMIC: Medium🔗 10.2174/0113895575434105260102065611
Translational — Mixed (Lab + Clinical)
Rhodiola sacra Protects Against Hippocampal Neuronal Apoptosis in Chronic Cerebral Ischemia via SIRT1-Driven Mitochondrial Biogenesis.
An integrated strategy including chemical profiling, network pharmacology and experimental evaluation was used to investigate the effects of Rubia yunnanensis water decoction on vascular dementia.
👤 Cheng J, Cheng C, Cheng L, Cheng G, Cheng X, Cheng P et al.📗 Pak J Pharm Sci (2026)🔴 Low Potential🌍 LMIC: Medium🔗 10.36721/PJPS.2026.39.5.REG.14029.1
Translational — Mixed (Lab + Clinical)
Effects of Intrathecal Magnesium Administration on Neurologic Outcomes in a Porcine Model of Asphyxial Cardiac Arrest.
👤 Lee HY, Lee N, Lee WY, Lee Y, Lee H, Lee YH et al.📗 J Am Heart Assoc (2026)🟡 Medium Potential🌍 LMIC: Medium🔗 10.1161/JAHA.125.046439
Translational — Mixed (Lab + Clinical)
A review of research progress of mirror therapy in peripheral nerve injury.
👤 Duan C, Duan H, Duan X, Duan Y, Duan X📗 Front Neurol (2026)🔴 Low Potential🌍 LMIC: Medium🔗 10.3389/fneur.2026.1740020
In Vivo — Rodent Model
Adversarial AI reveals mechanisms and treatments for disorders of consciousness.
👤 Toker D, Toker ZS, Toker JA, Toker J, Toker J, Toker H et al.📗 Nat Neurosci (2026)🟢 High Potential🌍 LMIC: Medium🔗 10.1038/s41593-026-02220-4
Translational — Mixed (Lab + Clinical)
Protein phosphatase 2A methylation state impacts α-synucleinopathy in mouse models.
👤 Maddila S, Maddila K, Maddila J, Maddila J, Maddila F, Maddila RE et al.📗 Cell Death Discov (2026)🟡 Medium Potential🌍 LMIC: Medium🔗 10.1038/s41420-026-03045-7
Translational — Mixed (Lab + Clinical)
[Application and Effectiveness of Repetitive Transcranial Magnetic Stimulation (rTMS) in Post-Stroke Patients: Exploration of Nursing Care Roles and Application Guidelines].
👤 Li RY, Li YM📗 Hu Li Za Zhi (2026)🟢 High Potential🌍 LMIC: Medium🔗 10.6224/JN.26210
In Vitro (Cell/Tissue)
Nose-to-brain delivery of berberine-loaded nanoemulsion: Amelioration of brain targeting, behavioral, pharmacokinetic, and biodistribution insights for Alzheimer's intervention.
👤 Negi M, Negi E, Negi V, Negi R, Negi S📗 Biomater Adv (2026)🟢 High Potential🌍 LMIC: Medium🔗 10.1016/j.bioadv.2026.214835
Translational — Mixed (Lab + Clinical)
Clinical significance of miR-28-5p in ischemic stroke and its neuroprotective effect after ischemia-reperfusion injury.
👤 Li Z, Li J, Li H, Li S, Li Y📗 Gerontology (2026)🟢 High Potential🌍 LMIC: Medium🔗 10.1159/000551361
In Vivo — Rodent Model
Mild neonatal hypoxia targets synaptic maturation, disrupts adult hippocampal learning and memory and is associated with CK2-mediated loss of synaptic calcium-activated potassium channel KCNN2 activity.
👤 Riddle A, Riddle T, Riddle K, Riddle E, Riddle H, Riddle X et al.📗 J Neurosci (2026)🟢 High Potential🌍 LMIC: Medium🔗 10.1523/JNEUROSCI.1643-25.2026
Translational — Mixed (Lab + Clinical)
Newfangled Combination Azilsartan and Ceftriaxone Exhibited Potential Effects in In-Vitro and In-Vivo Models of Cerebral Ischemia: A Comprehensive Pharmacological Investigation.
Aquaporin-4 suppresses neuronal pyroptosis after ischemic stroke via the IκBα/NF-κB signaling pathway.
👤 Chu H, Chu J, Chu Q, Chu C📗 Front Immunol (2026)🔴 Low Potential🌍 LMIC: Medium🔗 10.3389/fimmu.2026.1778802
Translational — Mixed (Lab + Clinical)
DPP-4 inhibitors for preventing post-stroke cognitive impairment in diabetic patients with acute ischemic stroke: a retrospective cohort study.
👤 Fu H, Fu J, Fu J, Fu F📗 Am J Transl Res (2026)🟢 High Potential🌍 LMIC: Medium🔗 10.62347/PLKN4994
Translational — Mixed (Lab + Clinical)
IncRNAs transcriptomics elucidates the potential mechanism of Naoshuantong capsule in alleviating synaptic dysfunction in a murine model of cerebral ischemia/reperfusion injury.
👤 Song K, Song H, Song H, Song Y, Song Y, Song X et al.📗 Front Pharmacol (2026)🔴 Low Potential🌍 LMIC: Medium🔗 10.3389/fphar.2026.1722930
Translational — Mixed (Lab + Clinical)
Peripheral B cell populations tune spontaneous neuronal activity in the uninjured hippocampus after stroke.
👤 Ujas TA, Ujas NS, Ujas P, Ujas VO, Ujas J, Ujas X et al.📗 bioRxiv (2026)🔴 Low Potential🌍 LMIC: Medium🔗 10.64898/2026.03.02.709034
Translational — Mixed (Lab + Clinical)
Structural targeting of a familial variant of neuroserpin (Ser52Arg) by epigallocatechin gallate binding that reduces polymerization and enhances the tissue plasminogen activator inhibition.
👤 Ahmad T, Ahmad FK, Ahmad U, Ahmad S, Ahmad A, Ahmad L et al.📗 Biochim Biophys Acta Proteins Proteom (2026)🔴 Low Potential🌍 LMIC: Medium🔗 10.1016/j.bbapap.2026.141140
Translational — Mixed (Lab + Clinical)
Assessment of microvascularization is a reliable diagnostic criterion for cerebral ischemia in preterm newborns with oxidative-stress-related conditons.
👤 Zakrevskyy A, Zakrevskyy K📗 Neurol Res (2026)🟢 High Potential🌍 LMIC: Medium🔗 10.1080/01616412.2026.2647422
Translational — Mixed (Lab + Clinical)
Stroke in China: advances in prevention and management on the path to a healthy China.
👤 Wu S, Wu Y, Wu J, Wu CS, Wu Z, Wu PAG et al.📗 Lancet Neurol (2026)🟢 High Potential🌍 LMIC: Medium🔗 10.1016/S1474-4422(26)00009-8
Translational — Mixed (Lab + Clinical)
Akkermansia muciniphila in Central Nervous System Disorders: Mechanisms, Controversies, and Therapeutic Potential.
Spreading depolarization: A wave that precedes and drives cerebral ischemic cell death-Target for neuroprotection.
👤 Pensato U, Pensato JM, Pensato CL, Pensato JA, Pensato M, Pensato S et al.📗 J Cereb Blood Flow Metab (2026)🔴 Low Potential🌍 LMIC: Medium🔗 10.1177/0271678X261417186
Translational — Mixed (Lab + Clinical)
From maternal nutrition to neonatal neuroprotection: Passion fruit stilbenes in hypoxia-ischemia.
👤 Goudeneche P, Goudeneche I, Goudeneche MC, Goudeneche C, Goudeneche L, Goudeneche C et al.📗 Biomed Pharmacother (2026)🟡 Medium Potential🌍 LMIC: Medium🔗 10.1016/j.biopha.2026.119240
Translational — Mixed (Lab + Clinical)
[Oropharyngeal dysphagia as a neurogeriatric syndrome].
👤 Jung A, Jung B📗 Z Gerontol Geriatr (2026)🔴 Low Potential🌍 LMIC: Medium🔗 10.1007/s00391-026-02570-5
Translational — Mixed (Lab + Clinical)
Bio-inspired spatiotemporal cascade reaction liposome for ferroptosis treatment following subarachnoid hemorrhage.
👤 Peng Z, Peng XJ, Peng YL, Peng XL, Peng Y, Peng Y et al.📗 Mater Today Bio (2026)🔴 Low Potential🌍 LMIC: Medium🔗 10.1016/j.mtbio.2026.102979
Translational — Mixed (Lab + Clinical)
PRECISION study: impact of personalised cardiac anaesthesia and cerebral autoregulation on neurological outcomes in patients undergoing cardiac surgery - protocol for an international, multicentre, prospective cohort study.
👤 Gomes NV, Gomes H, Gomes E, Gomes J, Gomes C, Gomes M et al.📗 BMJ Open (2026)🟢 High Potential🌍 LMIC: Medium🔗 10.1136/bmjopen-2025-115288
Translational — Mixed (Lab + Clinical)
Effects of hypothalamic phospholipid treatment in three patients with neurological disorders: a case series.
👤 Labate A, Labate G📗 J Med Case Rep (2026)🟢 High Potential🌍 LMIC: Medium🔗 10.1186/s13256-026-05970-8
Translational — Mixed (Lab + Clinical)
Sox10 glial-neuron nuclear communication mediates anti-apoptosis neuroprotection after ischaemic stroke.
👤 Huang M, Huang X, Huang Y, Huang Z, Huang J, Huang Q et al.📗 Stroke Vasc Neurol (2026)🔴 Low Potential🌍 LMIC: Medium🔗 10.1136/svn-2025-004934
Translational — Mixed (Lab + Clinical)
Recent advances of nanoparticles for ischemic stroke therapy.
👤 Yun T, Yun Y, Yun Y, Yun P, Yun Y📗 Nanomedicine (Lond) (2026)🔴 Low Potential🌍 LMIC: Medium🔗 10.1080/17435889.2026.2644387
Translational — Mixed (Lab + Clinical)
Intranasal carvacrol nanoemulsion: Stroke imaging and neuroprotective study.
Remote Ischemic Conditioning for Acute Ischemic Stroke: The RICAIS Randomized Clinical Trial.
👤 Kitagawa K, Kitagawa K, Kitagawa R, Kitagawa K, Kitagawa M, Kitagawa S et al.📗 J Atheroscler Thromb (2026)🟢 High Potential🌍 LMIC: Medium🔗 10.5551/jat.66105
In Vivo — Rodent Model
Neuroprotective response against the onset of ischemic stroke by upregulation of histone H3Y99 sulfation.
👤 Jiang L, Jiang J, Jiang J, Jiang Y, Jiang R, Jiang D et al.📗 Cell Rep Med (2026)🟢 High Potential🌍 LMIC: Medium🔗 10.1016/j.xcrm.2026.102684
Translational — Mixed (Lab + Clinical)
Vitamin D and hypoxia-inducible factors signaling interplay: A hypothesis-driven review of therapeutic strategies for acute cerebral infarction.
👤 Yan X, Yan ZY, Yan SX, Yan T📗 Metab Brain Dis (2026)🔴 Low Potential🌍 LMIC: Medium🔗 10.1007/s11011-026-01820-0
Translational — Mixed (Lab + Clinical)
Timing-Dependent Cleavage of Interleukin-1 Receptor Antagonist by Alteplase Impairs Neuroprotection in Ischemic Stroke.
👤 Mosneag IE, Mosneag M, Mosneag E, Mosneag Y, Mosneag BR, Mosneag R et al.📗 Stroke (2026)🟢 High Potential🌍 LMIC: Medium🔗 10.1161/STROKEAHA.125.054941
Translational — Mixed (Lab + Clinical)
Pearl Powder Fluorescent Carbon Dots Alleviate Neuroinflammation in Cerebral Ischemia/Reperfusion Through Suppression of Anxa2/NF-κB Signaling Pathway.
👤 Borjigin P, Borjigin C, Borjigin R, Borjigin J, Borjigin Y, Borjigin Y et al.📗 Int J Nanomedicine (2026)🟡 Medium Potential🌍 LMIC: Medium🔗 10.2147/IJN.S567974
Translational — Mixed (Lab + Clinical)
Human iPSC-derived exosomes for amelioration of Huntington's disease through mitochondrial, synaptic, and anti-apoptotic mechanisms.
👤 Jahng S, Jahng N, Jahng J, Jahng BG, Jahng M, Jahng M📗 Biomed Pharmacother (2026)🟢 High Potential🌍 LMIC: Medium🔗 10.1016/j.biopha.2026.119217
Translational — Mixed (Lab + Clinical)
Biomarkers of stroke recovery using EEG-based resting-state functional connectivity: a systematic review.
👤 Napoli E, Napoli F, Napoli R, Napoli F, Napoli G, Napoli MS et al.📗 J Neuroeng Rehabil (2026)🔴 Low Potential🌍 LMIC: Medium🔗 10.1186/s12984-026-01928-5
Translational — Mixed (Lab + Clinical)
Application and Research Progress of BCI in Post-Stroke Psychiatric Disorders: A Narrative Review.
👤 Hu Z, Hu J, Hu K, Hu S, Hu J📗 Med Sci Monit (2026)🟢 High Potential🌍 LMIC: Medium🔗 10.12659/MSM.951399
Translational — Mixed (Lab + Clinical)
Propolis alleviates brain tissue damage and oxidative abnormalities in streptozotocin (STZ)-induced diabetes.
Insights into the potential pathogenesis and therapeutic implications of ferroptosis in brain microvascular endothelial cells during stroke.
👤 Qin W, Qin Y, Qin J, Qin Q, Qin G, Qin S et al.📗 Front Immunol (2026)🟡 Medium Potential🌍 LMIC: Medium🔗 10.3389/fimmu.2026.1787418
Translational — Mixed (Lab + Clinical)
Synergistic impact of immuno-nutritional and hypoxia-metabolic disturbances on post-stroke epilepsy: a "Two-Hit" prediction model and web-based risk calculator.
👤 Liu S, Liu R📗 Front Nutr (2026)🟢 High Potential🌍 LMIC: Medium🔗 10.3389/fnut.2026.1759899
Translational — Mixed (Lab + Clinical)
Delayed cerebral ischaemia after subarachnoid haemorrhage: pathophysiology, diagnosis and neurotherapeutic opportunities.
👤 Thilak S, Thilak P, Thilak E, Thilak S, Thilak R, Thilak C et al.📗 Discov Med (Singap) (2025)🔴 Low Potential🌍 LMIC: Medium🔗 10.1007/s44337-025-00302-z
Translational — Mixed (Lab + Clinical)
Neurorehabilitation needs a qualitative perspective: a case exemplar from stroke recovery and rehabilitation.
👤 Demers M, Demers CJ📗 Front Hum Neurosci (2026)🟢 High Potential🌍 LMIC: Medium🔗 10.3389/fnhum.2026.1707789
Translational — Mixed (Lab + Clinical)
AdipoRon alleviates cerebral ischemic injury through AMPK-dependent microglial autophagy and phenotypic modulation.
👤 Meng L, Meng J, Meng B, Meng F, Meng M, Meng H et al.📗 Mol Cell Neurosci (2026)🟡 Medium Potential🌍 LMIC: Medium🔗 10.1016/j.mcn.2026.104079
In Vivo — Rodent Model
A Comprehensive Review of the Phytochemical Constituents and Diverse Pharmacological Applications of Diospyros kaki (Persimmon) Across Traditional and Modern Medicine.
👤 Bin Emran T, Bin Emran MA, Bin Emran B, Bin Emran SH, Bin Emran TS, Bin Emran UVNV et al.📗 Curr Top Med Chem (2026)🟢 High Potential🌍 LMIC: Medium🔗 10.2174/0115680266412103251206082207
In Vivo — Rodent Model
Transcriptomic Changes Associated with Electroacupuncture in a DMCAO Model of Delayed Cognitive Impairment.
👤 Lu L, Lu W, Lu S, Lu C, Lu H, Lu J et al.📗 Curr Neurovasc Res (2026)🟢 High Potential🌍 LMIC: Medium🔗 10.2174/0115672026451292260213073458
Translational — Mixed (Lab + Clinical)
Trial of Edaravone for severe hypoxic ischemic encephalopathy in adults: a double-blind placebo-controlled study.
👤 Dong W, Dong W, Dong L, Dong L, Dong Y, Dong L et al.📗 J Adv Res (2026)🔴 Low Potential🌍 LMIC: Medium🔗 10.1016/j.jare.2026.03.014
Translational — Mixed (Lab + Clinical)
Pregnanolone Glutamate: A Dual-Fate Delivery System for Neuroactive Steroids in Perinatal Focal Cerebral Ischemia.
👤 Tsenov G, Tsenov I, Tsenov M, Tsenov V, Tsenov H, Tsenov E et al.📗 Int J Mol Sci (2026)🟡 Medium Potential🌍 LMIC: Medium🔗 10.3390/ijms27052506
Translational — Mixed (Lab + Clinical)
Cerebral Ischemia-Reperfusion Injury: Unraveling the Mitophagy-Oxidative Stress Axis for Neuroprotective Strategies.
👤 Zhou Y, Zhou B, Zhou T, Zhou Z, Zhou W📗 Int J Mol Sci (2026)🟡 Medium Potential🌍 LMIC: Medium🔗 10.3390/ijms27052448
Translational — Mixed (Lab + Clinical)
Molecular Mechanisms and Targeted Intervention Strategies of Calcium Overload in Ischemic Stroke.
👤 Jiang Y, Jiang G, Jiang S, Jiang Y, Jiang Q, Jiang M📗 Int J Mol Sci (2026)🟢 High Potential🌍 LMIC: Medium🔗 10.3390/ijms27052279
Translational — Mixed (Lab + Clinical)
Expression Patterns of T-Cell Intracellular Antigen 1 in Neurodegenerative Disorders and Stroke.
👤 Han J, Han H, Han T, Han Z, Han L📗 Int J Mol Sci (2026)🟡 Medium Potential🌍 LMIC: Medium🔗 10.3390/ijms27052252
Translational — Mixed (Lab + Clinical)
Visuo-Vestibular Virtual Reality-Based Training for People with Stroke: A Feasibility Study.
👤 Piermaria J, Piermaria D, Piermaria S, Piermaria G, Piermaria M, Piermaria R et al.📗 Healthcare (Basel) (2026)🟢 High Potential🌍 LMIC: Medium🔗 10.3390/healthcare14050625
Translational — Mixed (Lab + Clinical)
Anthocyanin-Rich Extracts from Bilberries and Blackcurrants in Human Health: A Narrative Review of Their Anti-Inflammatory and Antioxidant Effects.
👤 Escobar-Cervantes C, Escobar-Cervantes C, Escobar-Cervantes S, Escobar-Cervantes AE, Escobar-Cervantes M📗 J Clin Med (2026)🟢 High Potential🌍 LMIC: Medium🔗 10.3390/jcm15052083
In Vivo — Rodent Model
Glycolic Acid-Guided Intelligent Neurovascular Imaging: A Cross-Scale Platform for Real-Time Neuroprotection and Adaptive Stroke Imaging.
👤 Malczewski K, Malczewski R, Malczewski Z, Malczewski M📗 J Clin Med (2026)🟢 High Potential🌍 LMIC: Medium🔗 10.3390/jcm15051851
Translational — Mixed (Lab + Clinical)
Atrial Fibrillation and Cognitive Decline: A Systematic Review of Pathophysiological Mechanisms, Therapeutic Strategies, and Digital Health Technologies in Neuroprotection.
👤 Santamaria A, Santamaria C, Santamaria N, Santamaria M, Santamaria P, Santamaria R📗 J Clin Med (2026)🟢 High Potential🌍 LMIC: Medium🔗 10.3390/jcm15051744
Translational — Mixed (Lab + Clinical)
Glutamatergic cannabinoid receptor 1 confers neuroprotection against ischemic stroke by suppressing excitotoxicity and anoxic depolarization.
👤 Jiang Y, Jiang M, Jiang C, Jiang J, Jiang J, Jiang X et al.📗 Neuropharmacology (2026)🔴 Low Potential🌍 LMIC: Medium🔗 10.1016/j.neuropharm.2026.110926
Translational — Mixed (Lab + Clinical)
Vagus nerve stimulation to improve post-stroke motor function and activity.
👤 Everard G, Everard ID, Everard J, Everard DE, Everard SM, Everard HM et al.📗 Cochrane Database Syst Rev (2026)🟢 High Potential🌍 LMIC: Medium🔗 10.1002/14651858.CD015859.pub2
Translational — Mixed (Lab + Clinical)
Acute cardio-centric haemodynamic management preserves chronic cardiovascular function in pigs with high-thoracic spinal cord injury.
👤 Williams AM, Williams N, Williams K, Williams M, Williams E, Williams K et al.📗 J Physiol (2026)🟡 Medium Potential🌍 LMIC: Medium🔗 10.1113/JP288045
Translational — Mixed (Lab + Clinical)
Multi-target neuroprotection of carbon dots derived from Crinis Carbonisatus in multiple acute epilepsy model.
👤 Cheng K, Cheng J, Cheng X, Cheng Y, Cheng X, Cheng Y et al.📗 Front Mol Biosci (2026)🟡 Medium Potential🌍 LMIC: Medium🔗 10.3389/fmolb.2026.1772499
Translational — Mixed (Lab + Clinical)
Integrative neurobiological mechanisms of acupuncture in post-stroke cognitive impairment: from neurotransmission to brain network remodeling.
👤 Li W, Li L, Li W, Li H📗 Front Neurol (2026)🟢 High Potential🌍 LMIC: Medium🔗 10.3389/fneur.2026.1744242
Translational — Mixed (Lab + Clinical)
Ferroptosis-Driven Neuronal Damage Exacerbation in Diabetic Stroke: Implications of SLC7A11 Inhibition.
👤 Liu S, Liu M, Liu B, Liu M, Liu H, Liu M et al.📗 CNS Neurosci Ther (2026)🔴 Low Potential🌍 LMIC: Medium🔗 10.1002/cns.70830
Translational — Mixed (Lab + Clinical)
Dual-stiffness nanoparticles for compartment-specific drug delivery in stroke.
👤 Liu H, Liu J, Liu Y, Liu R, Liu Z, Liu Y et al.📗 Nat Commun (2026)🔴 Low Potential🌍 LMIC: Medium🔗 10.1038/s41467-026-70340-3
In Vivo — Rodent Model
Ginkgolide B attenuates post-stroke cognitive impairment via exosomal miR-299a-3p regulation of the TRIL/PI3K/AKT pathway.
👤 Zhao D, Zhao C, Zhao A, Zhao X📗 Int Immunopharmacol (2026)🟡 Medium Potential🌍 LMIC: Medium🔗 10.1016/j.intimp.2026.116479
In Vivo — Rodent Model
FGF20 alleviates neuroinflammation in ischemic stroke by modulating microglial polarization via TREM2-TLR4/NF-κB pathway.
👤 Zhu L, Zhu S, Zhu Z, Zhu M, Zhu M, Zhu L et al.📗 Cell Immunol (2026)🟡 Medium Potential🌍 LMIC: Medium🔗 10.1016/j.cellimm.2026.105095
Translational — Mixed (Lab + Clinical)
Dopamine receptors: Potential therapeutic targets for ischemia-reperfusion injury: A review.
Preparation of ROS-responsive baicalin liposomes and evaluation of their therapeutic effects on hemorrhagic stroke-induced brain injury.
👤 Luo B, Luo J, Luo J, Luo L, Luo J, Luo Y et al.📗 J Liposome Res (2026)🟢 High Potential🌍 LMIC: Medium🔗 10.1080/08982104.2026.2641478
Translational — Mixed (Lab + Clinical)
Protective and pathogenic: The Janus-faced role of cGAS-STING in the brain.
👤 Corona C, Corona C, Corona A, Corona RR📗 J Cereb Blood Flow Metab (2026)🟡 Medium Potential🌍 LMIC: Medium🔗 10.1177/0271678X261427904
Translational — Mixed (Lab + Clinical)
A perspective on the potential role of remote ischemic conditioning in post-stroke depression: Mechanisms and future directions.
👤 Zhang H, Zhang R, Zhang S, Zhang S, Zhang X, Zhang S et al.📗 J Cereb Blood Flow Metab (2026)🟢 High Potential🌍 LMIC: Medium🔗 10.1177/0271678X261426923
Translational — Mixed (Lab + Clinical)
Catheter-Based Focal Hypothermia With Endovascular Reperfusion in Acute Anterior Circulation Large Artery Occlusion Stroke (CHILL-ART): A Randomized Controlled Trial Protocol.
👤 Sun W, Sun X, Sun M, Sun D, Sun Y, Sun L et al.📗 Stroke Vasc Interv Neurol (2026)🟢 High Potential🌍 LMIC: Medium🔗 10.1161/SVIN.125.002058
Translational — Mixed (Lab + Clinical)
Neuroprotective effects of therapeutic hypothermia by CiteSpace-based bibliometric analysis.
👤 Jia X, Jia X, Jia X, Jia Y, Jia E, Jia X et al.📗 Brain Circ (2026)🔴 Low Potential🌍 LMIC: Medium🔗 10.4103/bc.bc_47_24
Translational — Mixed (Lab + Clinical)
Remote ischemic conditioning: A bibliometric analysis.
👤 Mei Q, Mei H, Mei Y, Mei Z, Mei J, Mei X et al.📗 Brain Circ (2026)🔴 Low Potential🌍 LMIC: Medium🔗 10.4103/bc.bc_44_24
Translational — Mixed (Lab + Clinical)
Effect of Acute Intracranial Stenting in Patients With Successful Reperfusion Following Large-Vessel Occlusion Secondary to Intracranial Atherosclerosis: Secondary Analyses of the RESCUE-ICAS Study.
👤 Nguyen S, Nguyen A, Nguyen E, Nguyen MA, Nguyen V, Nguyen F et al.📗 Stroke Vasc Interv Neurol (2026)🟢 High Potential🌍 LMIC: Medium🔗 10.1161/SVIN.125.001841
In Vitro (Cell/Tissue)
[Salidroside suppresses ferroptosis in HT22 cells following oxygen-glucose deprivation/reoxygenation through regulation of non-ubiquitinated FUNDC1-dependent mitophagy pathway].
👤 DU QS, DU J📗 Zhongguo Zhong Yao Za Zhi (2026)🟡 Medium Potential🌍 LMIC: Medium🔗 10.19540/j.cnki.cjcmm.20250902.401
In Vivo — Rodent Model
[Naotaifang alleviates cerebral ischemia-reperfusion injury by inhibiting neuronal ferroptosis and pyroptosis through Nrf2 regulation].
👤 Wang WF, Wang J, Wang XL, Wang HF, Wang T, Wang XA et al.📗 Zhongguo Zhong Yao Za Zhi (2026)🟡 Medium Potential🌍 LMIC: Medium🔗 10.19540/j.cnki.cjcmm.20251021.901
Translational — Mixed (Lab + Clinical)
Astrocytic Mitochondria Transplantation Rescues Neuron Loss and Dendritic Injuries in Acute Cerebral Ischemic Stroke Mouse Model by Flexibly Regulating Mitochondria Dynamics.
👤 Bian N, Bian J, Bian L, Bian J, Bian L, Bian B et al.📗 Ann Neurol (2026)🔴 Low Potential🌍 LMIC: Medium🔗 10.1002/ana.78197
Translational — Mixed (Lab + Clinical)
BDNF Val66Met polymorphism modulates early TMS-EEG plasticity and rTMS efficacy in patients with anterior circulation ischemic stroke.
Feasibility and User Experience of Immersive Virtual Reality-Based Rehabilitation in Patients With Stroke: Single-Arm Pretest-Posttest Pilot Study.
👤 Arlati S, Arlati M, Arlati I, Arlati E, Arlati M, Arlati M et al.📗 JMIR Serious Games (2026)🟢 High Potential🌍 LMIC: Medium🔗 10.2196/79584
In Vitro (Cell/Tissue)
Neuroprotective Effects of Furanoditerpenes from Spongia (Spongia) Tubulifera through Cyclophilin D Modulation against Ischemia/Reperfusion Injury in BV2 Microglial Cells.
👤 Castedo N, Castedo A, Castedo R, Castedo D, Castedo L, Castedo J et al.📗 ACS Chem Neurosci (2026)🔴 Low Potential🌍 LMIC: Medium🔗 10.1021/acschemneuro.5c00949
In Vivo — Rodent Model
Discovery and Evaluation of N-Arylindole-Based GluN2B-NMDAR Antagonists with Reduced Cardiotoxicity for the Treatment of Ischemic Stroke.
👤 Zhang Z, Zhang K, Zhang Z, Zhang S, Zhang Y, Zhang X et al.📗 J Med Chem (2026)🟡 Medium Potential🌍 LMIC: Medium🔗 10.1021/acs.jmedchem.5c03741
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🇺🇸 NIH Fogarty International Center
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